Paper | Design | Variables | File |
Gregoriou et al | Two sequences, two periods,two treatments | group,patient,period,treat,response | Greg.txt |
Cohlen et al | Two sequences,six periods, two alternating treatments | group,patient, period2-period6,treatment,response, period | Cohlen.txt |
NB For the Cohlen data, dummy variables for periods (labelled "period2"-"period6") are included in case the period is to be treated as a factor. However, in case it is desired to treat period as a continuous variable this is also included and labelled "period".
Package | Data-set | Method | Link |
GenStat® | Gregoriou | Mantel-Haenszel | GregoriouMH.gen |
SAS® | Gregoriou | Ezzett and Whitehead random effects | Gregoriou.sas |
GenStat® | Gregoriou | Lee and Nelder HGLM | GregoriouHGLM.gen |
R | Gregoriou | Ezzett and Whitehead random effects | GregoriouR_lmer.txt |
WinBUGS | Gregoriou | Bayesian random effects | GregBUGS.txt |
SAS® | Cohlen | Ezzett and Whitehead random effect | Cohlen.sas |
GenStat® | Cohlen | Lee & Nelder HGLM | CohlenHGLM.gen |
R | Cohlen | Ezzett and Whitehead random effect | CohlenR_lmer.txt |
WinBUGS | Cohlen | Bayesian random effects | CohlBUGS.txt |
NB The SAS®and R programs for the Gregoriou and Cohlen data sets make reference to external data files Greg.txt and Cohlen.txt The user will have to set the file path appropriately in these programs. For the various winBUGS programs, different models and starting values etc are include in two text files, one for each dataset. The user will have to cut and paste these into a winBUGS program. The GenStat® programs are self-contained.
Cohlen, BJ, te Velde, ER, van Kooij, RJ, Looman, CW, Habbema, JD. Controlled ovarian hyperstimulation and intrauterine insemination for treating male subfertility: a controlled study, Hum Reprod 1998; 13: 1553-1558.
Gregoriou, O, Vitoratos, N, Papadias, C, Konidaris, S, Gargaropoulos, A, Rizos, D. Pregnancy rates in gonadotrophin stimulated cycles with timed intercourse or intrauterine insemination for the treatment of male subfertility, Eur J Obstet Gynecol Reprod Biol 1996; 64: 213-216.